What is the main site of infection for Enterobius vermicularis?

Enterobius vermicularis, commonly known as the pinworm, primarily infects the human intestines, with a particular emphasis on the cecum. This site is significant because it is where the adult worms reside and mature. The female pinworms migrate to the anal region, typically at night, to lay their eggs, which is a key factor in the transmission cycle. The focus on the cecum aligns with the pinworm's life cycle, where they thrive in the intestinal environment. Understanding this specific site of infection is critical for effective diagnosis and management of pinworm infections, which are common, especially in children.